Lattoferrina 200 Immuno 30 Stick Pack PromoPharma

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Kuipers ME, de Vries HG, Eikelboom MC, Meijer DK, Swart PJ (November 1999). "Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates". Antimicrobial Agents and Chemotherapy. 43 (11): 2635–41. doi: 10.1128/AAC.43.11.2635. PMC 89536. PMID 10543740. Mazurier J, Spik G (May 1980). "Comparative study of the iron-binding properties of human transferrins. I. Complete and sequential iron saturation and desaturation of the lactotransferrin". Biochimica et Biophysica Acta. 629 (2): 399–408. doi: 10.1016/0304-4165(80)90112-9. PMID 6770907.

Karns K, Herr AE (November 2011). "Human tear protein analysis enabled by an alkaline microfluidic homogeneous immunoassay". Analytical Chemistry. 83 (21): 8115–22. doi: 10.1021/ac202061v. PMID 21910436. Lactoferrin supplements reduce the risk of respiratory tract infections, based on a recent meta-analysis of randomized controlled trials. [9] As with any supplements sold online, quality may be an issue because nutritional supplement production quality controls are not subject to the same strict regulatory process as medicines. [10] History [ edit ] Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. Levay PF, Viljoen M (1995). "Lactoferrin: a general review". Haematologica. 80 (3): 252–67. PMID 7672721.Esistono anche evidenze circa un possibile ruolo della lattoferrina come agente antitumorale, dimostrato in numerose occasioni su tumori chimicamente indotti in ratti da laboratorio. Shortly after the emergence of COVID-19 in China, causing a global health crisis on a scale that has not been evidence in the last century ( 8). In the first days of January 2020, the reported number of patients that were diagnosed with COVID-19 infection was reported to be only 41 ( 9). Just within a few weeks, on January 30th, 2020, WHO declared the outbreak of COVID-19 as a Public Health Emergency of International Concern (PHEIC) ( 10). On July 8th, 2020, the coronavirus spread across 216 cities worldwide. Globally, as of 28th June 2022, there have been 542,188,789 confirmed cases of COVID-19 including 6,239,275 deaths, reported to WHO. Harmsen MC, Swart PJ, de Bethune MP, et al. Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro. J Infect Dis 1995;172:380-8. View abstract. Iwasa M, Kaito M, Ikoma J, et al. Lactoferrin inhibits hepatitis C virus viremia in chronic hepatitis C patients with high viral loads and HCV genotype 1b. Am J Gastroenterol 2002;97:766-7. Lactoferrin ( LF), also known as lactotransferrin ( LTF), is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin is also present in secondary granules of PMNs and is secreted by some acinar cells. Lactoferrin can be purified from milk or produced recombinantly. Human colostrum ( "first milk") has the highest concentration, followed by human milk, then cow milk (150mg/L). [5]

The lactoferrin receptor plays an important role in the internalization of lactoferrin; it also facilitates absorption of iron ions by lactoferrin. It was shown that gene expression increases with age in the duodenum and decreases in the jejunum. [34]Due to Lf's critical and clear influence on many infections, the mechanisms behind this antiviral characteristic must be investigated in detail. The potential mechanisms that Lf might possess can point to evidence and explanation of Lf's prevention effect on SARS-CoV-2. In addition, Lf not only carries potential treatment agents against SARS-CoV-2 infection, but it also has a specialty in recovery with its influence on the overall immune system. In the future, Lf not only can be used as a therapeutic agent, but also can be used as a recovery supplement for patients infected with COVID-19. Pammi M, Suresh G. Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants. Cochrane Database Syst Rev. 2020 Mar 31;3(3):CD007137. View abstract. At least 60 gene sequences of lactoferrin have been characterized in 11 species of mammals. [15] In most species, stop codon is TAA, and TGA in Mus musculus. Deletions, insertions and mutations of stop codons affect the coding part and its length varies between 2,055 and 2,190 nucleotide pairs. Gene polymorphism between species is much more diverse than the intraspecific polymorphism of lactoferrin. There are differences in amino acid sequences: 8 in Homo sapiens, 6 in Mus musculus, 6 in Capra hircus, 10 in Bos taurus and 20 in Sus scrofa. This variation may indicate functional differences between different types of lactoferrin. [15] Low quality evidence suggests that oral lactoferrin supplementation with or without the addition of a probiotic may decrease late onset of sepsis and necrotizing enterocolitis (stage II or III) in preterm infants with no adverse effects. [79] In diagnosis [ edit ]